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H1016 Section on Surgery - Rosenkrantz Competition -- Basic Science

This session comprises the best abstracts submitted to the 2014 AAP SoSU focusing on basic science investigations in the field of pediatric surgery.
Saturday, October 11, 2014: 7:15 AM-8:45 AM
Marriott Hall 3 (San Diego Marriott Marquis )
Session Moderators:
Elizabeth A. Beierle, MD , Cynthia D. Downard, M.D., M.M.Sc. and Harold Lovvorn, MD, FACS, FAAP
7:15 AM


IGF Promotes Intestinal Adaptation in a Zebrafish Model of Short Bowel Syndrome
Christa N Grant, MD, Children's Hospital Los Angeles; KathyAnn Schall, MD, Children's Hospital Los Angeles; Daniel Levin, MD, Children's Hospital Los Angeles; Denise Al Alam, PhD, Children's Hospital Los Angeles; Ching-Ling Lien, PhD, Children's Hospital, Los Angeles; Tracy Grikscheit, MD, FAAP, Children's Hospital Los Angeles
7:21 AM


Antenatal Retinoic Acid Administration Increases Trophoblastic Retinol-Binding Protein Dependent Retinol Transport in the Nitrofen Model of Congenital Diaphragmatic Hernia
Balazs Kutasy, National Children's Research Centre; Hiromizu Takahashi, National Children's Research Centre; Florian Friedmacher, National Children's Research Centre; Lara Pes, School of Chemistry & Chemical Biology College of Life Science, University College of Dublin; Takashi Doi, National Children's Research Centre; Francesca Paradisi, Centre for Synthesis & Chemical Biology, School of Chemistry & Chemical Biology, University College Dublin; Prem Puri, National Children's Research Centre
7:27 AM


Altered Distribution of Small-Conductance Ca2+-Activated K+ Channel SK3 in Hirschsprung's Disease
David Coyle, National Children's Research Centre; Anne-Marie O'Donnell, National Children's Research Centre; Prem Puri, National Children's Research Centre
7:33 AM


The Effect of Impaired Angiogenesis on Intestinal Function Following Massive Small Bowel Resection
Jose L. Diaz-Miron, MD, Washington University School of Medicine, St. Louis Children's Hospital; Raphael Sun, MD, Washington University School of Medicine, St. Louis Children's Hospital; Pamela Choi, MD, Washington University School of Medicine, St. Louis Children's Hospital; Joshua Sommovilla, MD, Washington University School of Medicine, St. Louis Children's Hospital; Jun Guo, PhD, Washington University School of Medicine, St. Louis Children's Hospital; Christopher R. Erwin, PhD, Washington University School of Medicine, St. Louis Children's Hospital; Junjie Mei, PhD, The Children's Hospital of Philadelphia; G. Scott Worthen, MD, The Children's Hospital of Philadelphia; Brad W. Warner, MD, Washington University School of Medicine, St. Louis Children's Hospital
7:39 AM


Trans-Amniotic Stem Cell Therapy (TRASCET) Minimizes Chiari-II Malformation in Experimental Spina Bifida
Beatrice Dionigi, MD, Boston Children's Hospital and Harvard Medical School; Joseph Brazzo III, BS, Boston Children's Hospital and Harvard Medical School; Azra Ahmed, BS, Boston Children's Hospital and Harvard Medical School; Christina Feng, MD, Boston Children's Hospital and Harvard Medical School; Yaotang Wu, PhD, Boston Children's Hospital and Harvard Medical School; David Zurakowski, PhD, Boston Children's Hospital and Harvard Medical School; Dario Fauza, MD, PhD, FAAP, Boston Children's Hospital and Harvard Medical School
7:45 AM


Both Epidermal Growth Factor and Insulin-like Growth Factor Receptors Are Dispensable for Structural Adaptation after Massive Small Bowel Resection
Raphael C. Sun, MD, Washington University School of Medicine, St. Louis Children's Hospital; Jose L. Diaz-Miron, MD, Washington University School of Medicine, St. Louis Children's Hospital; Pamela Choi, MD, Washington University School of Medicine, St. Louis Children's Hospital; Joshua Sommovilla, MD, Washington University School of Medicine, St. Louis Children's Hospital; Jun Guo, PhD, Washington University School of Medicine, St. Louis Children's Hospital; Christopher R. Erwin, PhD, Washington University School of Medicine, St. Louis Children's Hospital; Brad W. Warner, MD, Washington University School of Medicine, St. Louis Children's Hospital
7:51 AM


A Novel Method of Esophageal Lengthening in a Large Animal Model of Long-Gap Esophageal Atresia
Veronica F. Sullins, MD, Harbor-UCLA Medical Center; Peter K. Traum, MD, Harbor-UCLA Medical Center; Samuel W. French, MD, Harbor-UCLA Medical Center; Benjamin M. Wu, DDS, PhD, University of California, Los Angeles; James C. Y. Dunn, MD, PhD, David Geffen School of Medicine, University of California, Los Angeles, California; Steven L. Lee, MD, Harbor-UCLA Medical Center
7:57 AM


Absence of Intestinal Alkaline Phosphatase Leads to Neonatal Intestinal Inflammation
Nathan P Heinzerling, MD, Medical College of Wisconsin/Children's Hospital of Wisconsin; Jocelyn C. Miller, BA, Medical College of Wisconsin; Aron Geurts, PhD, Medical College of Wisconsin; Scott R. Welak, M.D., Medical College of Wisconsin; Katherine Fredrich, BA, Medical College of Wisconsin/Children's Hospital of Wisconsin; David M. Gourlay, MD, Medical College of Wisconsin
8:03 AM


Repeated Mechanical Lengthening of Intestinal Segments in a Novel Model
Andrew Scott, MD, David Geffen School of Medicine, University of California, Los Angeles, California; Veronica F. Sullins, MD, David Geffen School of Medicine, University of California, Los Angeles, California; Doug Steinberger, MD, University of California, Los Angeles, California; Justin P. Wagner, MD, David Geffen School of Medicine, University of California, Los Angeles, California; Elvin K. Chiang, BS, David Geffen School of Medicine, University of California, Los Angeles, California; Steven L. Lee, MD, David Geffen School of Medicine, University of California, Los Angeles, California; Benjamin M. Wu, DDS, PhD, University of California, Los Angeles; James C. Y. Dunn, MD, PhD, David Geffen School of Medicine, University of California, Los Angeles, California
8:09 AM


Local Chemotherapeutic Treatment of Neuroblastoma Using Controlled Release Silk Films in an Orthotopic Xenograft Mouse Model
Bill Chiu, MD, University of Illinois at Chicago; Jeannine Coburn, PhD, Tufts University; Philipp Seib, PhD, University of Strathclyde; Ilona Konrad, Tufts University; Brian P Blackwood, MD, Rush University; Monika Pilichowska, MD, PhD, Tufts Medical Center; Alain Charest, MSc, PhD, Tufts Medical Center; David L. Kaplan, PhD, Tufts University
8:15 AM


Increased Activation of PIM-1 and Phosphorylated STAT3 Expression in the Pulmonary Vasculature of Experimental Congenital Diaphragmatic Hernia
Alejandro D. Hofmann, MD, National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland; Florian Friedmacher, MD, MSc, National Children's Research Centre, Our Lady's Children's Hospital, Dublin; Manuela Hunziker, MD, National Children's Research Centre, Our Lady's Children's Hospital, Dublin; Toshiaki Takahashi, MD, National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland; Johannes W. Duess, MD, National Children's Research Centre, Our Lady's Children's Hospital; Jan-Hendrik Gosemann, MD, National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland; Prem Puri, MS, FRCS, FRCS (ED), FACS, FAAP (Hon.), National Children's Research Centre, Our Lady's Children's Hospital, Dublin
8:21 AM


Extraluminal Distraction Enterogenesis Using a Shape Memory Polymer
Jeremy G. Fisher, MD, Center for Advanced Intestinal Rehabilitation, Department of Surgery, Boston Children's Hospital and Harvard Medical School; Eric A. Sparks, MD, Center for Advanced Intestinal Rehabilitation, Department of Surgery; Faraz A. Khan, M.D., Center for Advanced Intestinal Rehabilitation, Department of Surgery; Beatrice Dionigi, MD, Boston Children's Hospital and Harvard Medical School; Hao Wu, MD, Department of Pathology; Azra Ahmed, BS, Department of Surgery, Boston Children's Hospital, Harvard Medical School; Dario Fauza, MD, PhD, FAAP, Boston Children's Hospital, Harvard Medical School; Biren P. Modi, M.D., Center for Advanced Intestinal Rehabilitation, Department of Surgery; Tom Jaksic, MD, PhD, Center for Advanced Intestinal Rehabilitation, Department of Surgery
8:27 AM


Placental Drug Delivery for Treatment of Congenital Hematopoietic Disorders
S. Christopher Derderian, MD, University of California, Fetal Treatment Center, Division of Pediatric Surgery; P. Wais Moradi, B.S., University of California San Francisco; Tippi MacKenzie, MD, University of California, Fetal Treatment Center, Division of Pediatric Surgery
8:33 AM


Respiratory Distress Syndrome Induced By Mesenchyme-Specific Inhibition of Vascular Endothelial Growth Factor (VEGF) in Neonatal Mice
Ryan G. Spurrier, MD, Children's Hospital Los Angeles; Daniel Levin, MD, Children's Hospital Los Angeles; Salvador M. Garcia, BS, Children's Hospital Los Angeles; Michael J. Hiatt, PhD, Children's Hospital Los Angeles; Raghava R. Reddy, PhD, Children's Hospital Los Angeles; Xiaogang Hou, PhD, Children's Hospital Los Angeles; Sonia Navarro, MS, Children's Hospital Los Angeles; Barbara Driscoll, PH.D., Saban Research Institute and Childrens Hospital Los Angeles; Tracy Grikscheit, MD, FAAP, Children's Hospital Los Angeles
8:39 AM


Age Does Matter: A Comparison of Placenta-Derived Stem Cells for in Utero Repair of Fetal Myelomeningocele in the Fetal Lamb Model
Erin G. Brown, MD, University of California, Davis; Benjamin A. Keller, MD, University of California, Davis; Christopher D. Pivetti, University of California, Davis; Lee Lankford, University of California, Davis; Aijun Wang, PhD, University of California, Davis; Diana L. Farmer, MD, University of California, Davis
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